五、丁学屏医案..........................................................................................................340
六、栗锦迁医案..........................................................................................................342
七、张素清医案..........................................................................................................342
第三章　展望篇...........................................................................................................................344
**节　糖尿病合并冠心病病证结合诊疗方案...................................................................344
一、研究对象..............................................................................................................344
二、研究方法..............................................................................................................345
三、结果......................................................................................................................347
四、讨论......................................................................................................................380
五、结论......................................................................................................................386
第二节　益气活血方治疗糖尿病心肌病的疗效和有效组分处方优化..............................386
一、丹参饮抗糖尿病心肌病大鼠心肌纤维化疗效及分子机制..............................387
二、生脉散抑制高糖环境心肌细胞凋亡疗效及分子机制......................................406
三、基于均匀设计抗糖尿病心肌纤维化中药有效组分处方优化..........................418
四、益气活血方有效组分配伍验证研究..................................................................447
第三节　 2型糖尿病合并冠心病证候规律及益气活血方抗心肌间质纤维化的
分子机制.....................................................................................................................458
一、基于结构化住院病历数据库的2型糖尿病合并冠心病中医证治规律..........458
二、益气活血方抗心肌纤维化分子机制..................................................................473
第四节　糖尿病心脏病相关研究进展....................................................................................506
一、研究方法..............................................................................................................506
二、糖尿病心脏病动物模型研究进展......................................................................525
三、流行病学..............................................................................................................535
四、相关诊疗进展......................................................................................................536

参考文献.......................................................................................................................................547
附录一　缩略语表.......................................................................................................................567
附录二　方剂索引.......................................................................................................................573
附录三　糖尿病、糖尿病前期与心血管疾病指南...................................................................578
一、绪论......................................................................................................................578
二、引言......................................................................................................................578
三、血糖代谢异常和心血管疾病..............................................................................579
四、糖尿病发生心血管疾病的分子基础..................................................................584
五、血糖紊乱患者心血管风险评估..........................................................................586
六、在糖尿病患者中预防心脑血管疾病..................................................................588
七、糖尿病患者稳定型和不稳定型冠状动脉疾病的管理......................................604
八、心力衰竭与糖尿病..............................................................................................613
九、心律失常：心房纤颤与心源性猝死..................................................................619
十、外周血管和脑血管疾病......................................................................................624
十一、眼睛和肾脏等部位的微血管病变 ..................................................................628
十二、以患者为中心的医疗护理..............................................................................631
附录四　糖尿病合并心脏病中医诊疗标准...............................................................................633
一、范围......................................................................................................................633

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