比较蛋白质组学的生物信息学-(影印版) 本书特色
随着生命科学和临床应用蛋白质组学技术的快速发展,许多生物信息学的研究方法、数据库、软件工具已经可以用于支持比较蛋白质组学的研究。《比较蛋白质组学的生物信息学(影印版)》分为3个主要部分,包括与比较蛋白质组学相关的基础生物信息学框架、蛋白质组学数据分析的生物信息学数据库和工具,以及在系统生物学背景下的比较蛋白质组学关于整合生物信息的系统学和研究方法。本书提供了详细的操作建议,逐步地描述操作过程,务求让使用者在实验室获得*佳的实验结果。
比较蛋白质组学的生物信息学-(影印版) 内容简介
蛋白质组学技术的飞速发展,催生了海量数据。这些数据的收集、存储、整理和分析给生物信息学带来了挑战。在这些方面,国内相关的生物信息学研究有了一定的研究基础,但在相关知识的普及教育方面非常欠缺,*明显的是国内尚没有一本蛋白质组信息学的专著。国内正需要一本这种深入浅出、全方位介绍比较蛋白质组数据处理的科学读本,能在基础与应用层面上起到指引的作用。但凡科学离不开技术,但凡数据离不开分析。特别在眼下生命科学研究组学化、组学研究系统化的大趋势下,国内蛋白质组学的瓶颈已不再是仪器和实验,而是实验设计和数据分析。引入该书对加强、提升我国蛋白组学数据分析能力,着力于突破目前的瓶颈会起到巨大的推动作用。
——贺福初军事医学科学院
比较蛋白质组学的生物信息学-(影印版) 目录
prefacecontributorspart i: bioinformatics framework for comparative proteomics 1 protein bioinformatics databases and resources churning chen, hongzhan huang, and cathy h. wu 2 a guide to uniprot for protein scientists claire o'donovan and rolf apweiler 3 interpro protein classification jennifer mcdowall and sarah hunter 4 reactome knowledgebase of human biological pathways and processes peter d'eustachio 5 efip: a tool for mining functional impact of phosphorylation from literature cecilia n. arighi, amy y. siu, catalina o. tudor, jules a. nchoutrnboube, cathy it. wu, and vijay k. shanker 6 a tutorial on protein ontology resources for proteomic studies cecilia n. arighi 7 structure-guided rule-based annotation. of protein functional sites in uniprot knowledgebase sona vasudevan, c.r. vinayaka, darren a. natale, hongzhan huang, robel y. kahsay, and cathy h. wupart ii: proteomic bioinformatics 8 modeling mass spectrometry-based protein analysis jan eriksson and david feny 9 protein identification from tandem mass spectra by database searching nathan j. edwards 10 lc-ms data analysis for differential protein expression detection rency s. varghese and habtorn w. ressom 11 protein identification by spectral networks analysis nuno bandeira 12 software pipeline and data analysis for ms/ms proteomics: the trans-proteomic pipeline andrew keller and david shteynberg 13 analysis of high-throughput elisa microarray data amanda m. white, don s. daly, and richard c. zangar 14 proteomics databases and repositories lennart martens 15 preparing molecular interaction data for publication sandra orchard and henning hermjakob 16 submitting proteomics data to pride using pride converter harald barsnes, juan antonio vizcalno, florian reisinger, ingvar eidhammer, and lennart martens 17 automated data integration and determination of posttranslational modifications with the protein inferenceengine stuart r. jefferys and morgan c. giddings 18 an integrated top-down and bottom-up strategy for characterization of protein isoforms and modifications si wu, nikola toli, zhixin tian, errol w. robinson, and ljiljana paa- tolipart iii: comparative proteomics in systems biology 19 phosphoproteome resource for systems biology research bernd bodenmiller and ruedi aebersold 20 protein-centric data integration for functional analysis of comparative proteomics data peter b. mcgarvey, jian zhang, darren a. natale, cathy h. wu, and hongzhan huang 21 integration of proteomic and metabolomic profiling as well as metabolic modeling for the functional analysis of metabolic networks patrick may, nils christian, oliver ebenhh, wolfram weckwerth, and dirk walther 22 time series proteome profiling catherine a. formolo, michelle mint4 asako takanohashi, kristy j. brown, adeline vanderver, brian halligan, and yetrib hathout index
比较蛋白质组学的生物信息学-(影印版) 作者简介
Cathy H. Wu
美国特拉华州纽瓦克市,特拉华大学,特拉华生物技术研究所计算机与信息科学系
Chuming Chen
美国特拉华州纽瓦克市,特拉华大学,特拉华生物技术研究所计算机与信息科学系